Gordon Guyatt, MD: Proper methods for meta-analyses
Produced and interviewed by Steven Greer, MD
Meta-analyses and other forms of systematic reviews of the medical literature to determining comparative effectiveness have grown in prevalence and prestige over the last decade. PCORI, AHRQ, The Cochrane Group, medical societies, and many other organizations have their own efforts to create reviews of clinical therapies. Not surprisingly, for-profit entities have also hijacked the process the create research to suit their needs.
In Part 1, Dr. Guyatt explains why this systematic reviews have grown, and discusses the major established guidelines for conducting such reviews. He mentions AMSTAR and The Cochrane Handbook as the best resources, in his opinion.
In Part 2, Dr. Guyatt mentions how the process for meta-analysis can be manipulated to create junk science data.
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